Antibiotic Prophylaxis for Cardiac Surgery

Cardiac Surgical Patients

Primary procedure

Teicoplanin (10mg/Kg, with a second dose to be given after 12 hours) plus a single dose of Gentamicin (3mg/Kg)*.

Repeat procedure (re-sternotomy)

Within 28 days of primary operation – Meropenem 1g TDS for 48hrs plus Teicoplanin (10mg/Kg with a second dose to be given after 12 hours) **

*If eGFR <20ml/min then discuss with microbiology

** If already received a dose of teicoplanin within the preceding 12 hours then ensure subsequent doses are delayed accordingly. (Teicoplanin not to be dosed more frequently than BD)

Teicoplanin dosing table (doses do not need to be adjusted for renal function)